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1

Ethidium bromide–dinucleotide complexes. Evidence for intercalation and sequence preferences in binding to double-stranded nucleic acids

Thomas R. Krugh, Frederick N. Wittlin, Stephen P. Cramer

Journal:

Year:

1975

Language:

english

File:

PDF, 746 KB

english, 1975

2

Resolution of electronic absorption bands and nucleotide binding processes in actinomycin D

Henary E. Auer, Barbara E. Pawlowski-Konopnicki, Yu-Chih Chen Chiao, Thomas R. Krugh

Journal:

Year:

1978

Language:

english

File:

PDF, 1.16 MB

english, 1978

3

7-Amino-actinomycin D complexes with deoxynucleotides as models for the binding of the drug to DNA

Yu-Chih Chen Chiao, K. Gurudath Rao, John W. Hook III, Thomas R. Krugh, Sisir K. Sengupta

Journal:

Year:

1979

Language:

english

File:

PDF, 798 KB

english, 1979

4

Large-scale purification of synthetic oligonucleotides and carcinogen-modified oligodeoxynucleotides on a reverse-phase polystyrene (PRP-1) column

Guanjin Huang, Thomas R. Krugh

Journal:

Analytical Biochemistry

Year:

1990

Language:

english

File:

PDF, 549 KB

english, 1990

5

Measurement of relaxation times by the adiabatic half passage (T1ϱ) technique

James W Neely, Thomas R Krugh

Journal:

Journal of Magnetic Resonance (1969)

Year:

1969

Language:

english

File:

PDF, 540 KB

english, 1969

6

Proton Fourier transform nmr spectroscopy in H2O solutions on a JEOL PFT-100. The WEFT, SWEFT, and VASE pulse sequences

Thomas R Krugh, William C Schaefer

Journal:

Journal of Magnetic Resonance (1969)

Year:

1969

Language:

english

File:

PDF, 631 KB

english, 1969

7

Proton fourier-transform NMR spectroscopy in H2O solutions

Eddie S Mooberry, Thomas R Krugh

Journal:

Journal of Magnetic Resonance (1969)

Year:

1969

Language:

english

File:

PDF, 246 KB

english, 1969

8

Single-cell partition analysis—A direct fluorescence technique for examining ligand-macromolecule interactions

David E. Graves, Thomas R. Krugh

Journal:

Analytical Biochemistry

Year:

1983

Language:

english

File:

PDF, 732 KB

english, 1983

9

Daunorubicin and adriamycin facilitate actinomycin D binding to poly(dA–dT)·poly(dA–dT)

KRUGH, THOMAS R., YOUNG, MICHAEL A.

Journal:

Year:

1977

File:

PDF, 217 KB

1977

10

Equilibrium binding of carcinogens and antitumor antibiotics to DNA: site selectivity, cooperativity, allosterism

Winkle, Stephen A., Krugh, Thomas R.

Journal:

Nucleic Acids Research

Year:

1981

Language:

english

File:

PDF, 491 KB

english, 1981

11

The absorption spectrum of actinomycin D. evidence for three transitions in the visible band

Henry E. Auer, Barbara E. Pawlowski-Konopnicki, Thomas R. Krugh

Journal:

Year:

1977

Language:

english

File:

PDF, 358 KB

english, 1977

12

Improved Nonrelapse Mortality and Infection Rate with Lower Dose of Antithymocyte Globulin in Patients Undergoing Reduced-Intensity Conditioning Allogeneic Transplantation for Hematologic Malignancies

Mehdi Hamadani, William Blum, Gary Phillips, Patrick Elder, Leslie Andritsos, Craig Hofmeister, Lynn O'Donnell, Rebecca Klisovic, Sam Penza, Ramiro Garzon, David Krugh, Thomas Lin, Thomas Bechtel, Don

Journal:

Biology of Blood and Marrow Transplantation

Year:

2009

Language:

english

File:

PDF, 262 KB

english, 2009

13

Nuclear magnetic resonance studies of hydrogen bonded complexes of oligonucleotides in aqueous solution. I. pdG-dC and pdG-dT

Thomas R. Krugh, Michael A. Young

Journal:

Biochemical and Biophysical Research Communications

Year:

1975

Language:

english

File:

PDF, 339 KB

english, 1975

14

Solute enhanced partition analysis—A novel method for measuring the binding of drugs to DNA

Thomas R. Krugh, Stephen A. Winkle, David E. Graves

Journal:

Biochemical and Biophysical Research Communications

Year:

1981

Language:

english

File:

PDF, 448 KB

english, 1981

15

2–Aminofluorene modified DNA duplex exists in two interchangeable conformations

Eckel, Linda M., Krugh, Thomas R.

Journal:

Natural Structural Biology

Year:

1994

File:

PDF, 1.22 MB

1994

16

Evidence for sequence preferences in the intercalative binding of ethidium bromide to dinucleoside monophosphates

Thomas R. Krugh, Christian G. Reinhardt

Journal:

Journal of Molecular Biology

Year:

1975

Language:

english

File:

PDF, 1.66 MB

english, 1975

17

GCCU) 2†,‡

Znosko, Brent M., Burkard, Mark E., Schroeder, Susan J., Krugh, Thomas R., Turner, Douglas H.

Journal:

Year:

2002

File:

PDF, 306 KB

2002

18

CUC) 2†,‡

Chen, Xiaoying, McDowell, Jeffrey A., Kierzek, Ryszard, Krugh, Thomas R., Turner, Douglas H.

Journal:

Year:

2000

Language:

english

File:

PDF, 194 KB

english, 2000

19

Structural Features and Thermodynamics of the J4/5 Loop from the Candida albicans and Candida dubliniensis Group I Introns †,‡

Znosko, Brent M., Kennedy, Scott D., Wille, Pamela C., Krugh, Thomas R., Turner, Douglas H.

Journal:

Year:

2004

Language:

english

File:

PDF, 611 KB

english, 2004

20

A comparative study of ethidium bromide complexes with dinucleotides and DNA: direct evidence for intercalation and nucleic acid sequence preferences

Reinhardt, Christian G., Krugh, Thomas R.

Journal:

Year:

1978

Language:

english

File:

PDF, 1.13 MB

english, 1978

21

The antitumor agent mitoxantrone binds cooperatively to DNA: evidence for heterogeneity in DNA conformation

Rosenberg, Leonard S., Carvlin, Mark J., Krugh, Thomas R.

Journal:

Year:

1986

Language:

english

File:

PDF, 880 KB

english, 1986

22

Ethidium binding to left-handed (Z) DNAs results in regions of right-handed DNA at the intercalation site

Walker, G. Terrance, Stone, Michael P., Krugh, Thomas R.

Journal:

Year:

1985

Language:

english

File:

PDF, 1.32 MB

english, 1985

23

Adriamycin and daunorubicin bind in a cooperative manner to deoxyribonucleic acid

Graves, David E., Krugh, Thomas R.

Journal:

Year:

1983

Language:

english

File:

PDF, 918 KB

english, 1983

24

Drug-DNA interactions

Krugh, Thomas R.

Journal:

Current Opinion in Structural Biology

Year:

1994

Language:

english

File:

PDF, 3.64 MB

english, 1994

25

Fluorescence-detected circular dichroism of ethidium bound to poly(dG-dC) and poly(dG-m5dC) under B- and Z-form conditions

Lamos, Michael L., Walker, G. Terrance, Krugh, Thomas R., Turner, Douglas H.

Journal:

Year:

1986

Language:

english

File:

PDF, 577 KB

english, 1986

26

Solution Structure of an RNA Internal Loop with Three Consecutive Sheared GA Pairs †,‡

Chen, Gang, Znosko, Brent M., Kennedy, Scott D., Krugh, Thomas R., Turner, Douglas H.

Journal:

Year:

2005

Language:

english

File:

PDF, 550 KB

english, 2005

27

An Alternating Sheared AA Pair and Elements of Stability for a Single Sheared Purine-Purine Pair Flanked by Sheared GA Pairs in RNA †,‡

Chen, Gang, Kennedy, Scott D., Qiao, Jing, Krugh, Thomas R., Turner, Douglas H.

Journal:

Year:

2006

Language:

english

File:

PDF, 748 KB

english, 2006

28

Association of Actinomycin D and Deoxyribodinucleotides as a Model for Binding of the Drug to DNA

Thomas R. Krugh

Journal:

Proceedings of the National Academy of Sciences

Year:

1972

Language:

english

File:

PDF, 621 KB

english, 1972

29

The NMR Structure of an Internal Loop from 23S Ribosomal RNA Differs from Its Structure in Crystals of 50S Ribosomal Subunits †,‡

Shankar, Neelaabh, Kennedy, Scott D., Chen, Gang, Krugh, Thomas R., Turner, Douglas H.

Journal:

Year:

2006

Language:

english

File:

PDF, 919 KB

english, 2006

30

Actinomycin D-deoxynucleotide complexes as models for the actinomycin D-DNA complex. Use of nuclear magnetic resonance to determine the stoichiometry and the geometry of the complexes

Krugh, Thomas R., Chen, Yu-Chih

Journal:

Year:

1975

Language:

english

File:

PDF, 1.24 MB

english, 1975

31

GCCU) 2†,‡

Znosko, Brent M., Burkard, Mark E., Krugh, Thomas R., Turner, Douglas H.

Journal:

Year:

2002

Language:

english

File:

PDF, 238 KB

english, 2002

32

Ethidium bromide complexes with self-complementary deoxytetranucleotides. Demonstration and discussion of sequence preferences in the intercalative binding of ethidium bromide

Kastrup, Rodney V., Young, Michael A., Krugh, Thomas R.

Journal:

Year:

1978

Language:

english

File:

PDF, 1.32 MB

english, 1978

33

Actinomycin D complexes with oligonucleotides as models for the binding of the drug to DNA. Paramagnetic induced relaxation experiments on drug-nucleic acid complexes

Chiao, Yu-Chih Chen, Krugh, Thomas R.

Journal:

Year:

1977

Language:

english

File:

PDF, 959 KB

english, 1977

34

Actinomycin D-deoxydinucleotide interactions as a model for binding of the drug to deoxyribonucleic acid. Proton magnetic resonance results

Krugh, Thomas R., Neely, James W.

Journal:

Year:

1973

Language:

english

File:

PDF, 1000 KB

english, 1973

35

Proton magnetic resonance studies of actinomycin D complexes with mixtures of nucleotides as models for the binding of the drug to DNA

Krugh, Thomas R., Mooberry, Eddie S., Chiao, Yu-Chih Chen

Journal:

Year:

1977

Language:

english

File:

PDF, 909 KB

english, 1977

36

Tautomerism of the nucleoside antibiotic formycin, as studied by carbon-13 nuclear magnetic resonance

Krugh, Thomas R.

Journal:

Journal of the American Chemical Society

Year:

1973

Language:

english

File:

PDF, 243 KB

english, 1973

37

The National Conferences on Undergraduate Research: Conference History and the Role of Chemistry

Werner, T. C., Lichter, Robert L., Krugh, Thomas R.

Journal:

Journal of Chemical Education

Year:

2001

Language:

english

File:

PDF, 88 KB

english, 2001

38

U GCU) 2 : Probing the Structural Features That Shape the Thermodynamic Stability of GA Pairs †,‡

Tolbert, Blanton S., Kennedy, Scott D., Schroeder, Susan J., Krugh, Thomas R., Turner, Douglas H.

Journal:

Year:

2007

Language:

english

File:

PDF, 815 KB

english, 2007

39

Hydrogen-bonded complexes of the ribodinucleoside monophosphates in aqueous solution. Proton magnetic resonance studies

Krugh, Thomas R., Laing, Jean W., Young, Michael A.

Journal:

Year:

1976

Language:

english

File:

PDF, 544 KB

english, 1976

40

Structural Characterization of Two Interchangeable Conformations of an N-2-Aminofluorene-Modified DNA Oligomer by NMR and Energy Minimization

Eckel, Linda M., Krugh, Thomas R.

Journal:

Year:

1994

Language:

english

File:

PDF, 2.32 MB

english, 1994

41

Structural characterization of an N-acetyl-2-aminofluorene (AAF) modified DNA oligomer by NMR, energy minimization, and molecular dynamics

O'Handley, Suzanne F., Sanford, David G., Xu, Rong, Lester, Cathy C., Hingerty, Brian E., Broyde, Suse, Krugh, Thomas R.

Journal:

Year:

1993

Language:

english

File:

PDF, 4.52 MB

english, 1993

42

Thermodynamic Stability and Structural Features of the J4/5 Loop in a Pneumocystis carinii Group I Intron †

Schroeder, Susan J., Fountain, Matthew A., Kennedy, Scott D., Lukavsky, Peter J., Puglisi, Joseph D., Krugh, Thomas R., Turner, Douglas H.

Journal:

Year:

2003

Language:

english

File:

PDF, 444 KB

english, 2003

43

Mapping of (.+-.)-anti-benzo[a]pyrene diol epoxide adducts to human c-Ha-ras1 protooncogene

Dittrich, Karen A., Krugh, Thomas R.

Journal:

Chemical Research in Toxicology

Year:

1991

Language:

english

File:

PDF, 1.10 MB

english, 1991

44

Interaction of drugs with Z-DNA: cooperative binding of actinomycin D or actinomine to the left-handed forms of poly(dG-dC).cntdot.poly(dG-dC) and poly(dG-m5dC).cntdot.poly(dG-m5dC) reverses the conformation of the helix

Walker, G. Terrance, Stone, Michael P., Krugh, Thomas R.

Journal:

Year:

1985

Language:

english

File:

PDF, 1.19 MB

english, 1985

45

Structural Features of a Six-Nucleotide RNA Hairpin Loop Found in Ribosomal RNA †

Fountain, Matthew A., Serra, Martin J., Krugh, Thomas R., Turner, Douglas H.

Journal:

Year:

1996

Language:

english

File:

PDF, 523 KB

english, 1996

46

Actinomycin D-mononucleotide interactions as studied by proton magnetic resonance

Krugh, Thomas R., Neely, James W.

Journal:

Year:

1973

Language:

english

File:

PDF, 1.97 MB

english, 1973

47

Structural Characterization of a (+)-trans-anti-Benzo[a]pyrene-DNA Adduct using NMR, Restrained Energy Minimization, and Molecular Dynamics

Fountain, Matthew A., Krugh, Thomas R.

Journal:

Year:

1995

Language:

english

File:

PDF, 1.84 MB

english, 1995

48

Two-dimensional NMR studies on the anthramycin-d(ATGCAT)2 adduct

Krugh, Thomas R., Graves, David E., Stone, Michael P.

Journal:

Year:

1989

Language:

english

File:

PDF, 1.31 MB

english, 1989

49

Proximity of the nucleoside monophosphate and triphosphate binding sites on deoxyribonucleic acid polymerase

Krugh, Thomas R.

Journal:

Year:

1971

Language:

english

File:

PDF, 707 KB

english, 1971

50

Proton magnetic resonance studies of double helical oligonucleotides. Effect of base sequence on the stability of deoxydinucleotide dimers

Young, Michael A., Krugh, Thomas R.

Journal:

Year:

1975

Language:

english

File:

PDF, 790 KB

english, 1975